Chemical Supply
Nucleoside Chemistry
- Nucleoside analogues and derivatives have been widely used as anti-tumor and anti-viral medicines. They are the basic units and precursors for oligonucleotide therapeutics such as siRNA, saRNA and mRNA. The modified nucleosides are also used in sequencing kits. Modification of the bases or sugar rings may significantly change the pharmacokinetics and pharmacodynamics properties of nucleoside molecules. Also it could lower the immunogenicity and improve the stability of oligonucleotides. Therefore, nucleoside analogues and derivatives play an important role for drug research.
- Sugar moiety modification including furanose, pyranose, carbocyclic, S-substituted rings, morpholine and acyclic rings
- Purine, pyrimidine based natural and unnatural bases with various glycosidic bonds
- Natural or modified monophosphates, diphosphates and triphosphates
- Phosphoramites (stock products shown as below), prodrugs and fluorescent nucleoside derivatives
- Fully equipped instrument facilities, such as NMR, LC-MS, HPLC, SFC, MPLC with quality control system which is able to support the need of high quality chemicals from mg to kg scale synthesis.
Nucleotides and Nucleosides
Phosphoramidites
2′-deoxy Monomer
2′-OMe Monomer
2′-F Monomer
2′-OMOE Monomer
LNA Monomer
UNA Monomer
2′-TBS Monomer
GNA Monomer
Dimer
Nucleoside Derivatives
Nucleotide Derivatives
Delivery Vectors
GalNAC and Lipids Delivery Systems
